A rapid review of the evidence of cost effectiveness of interventions to improve the oral health of 0-5-year olds. This document provides updated economic evidence on oral health prevention measures since the review published by NICE in 2014. It includes supervised tooth brushing, fluoride varnish, water fluoridation, provision of toothbrushes and paste, and interventions provided in home visits by health workers. This document is supplemented with an infographic which summarises the return on investment of the 5 interventions using modelling data.